Publications
Microsputterer with integrated ion-drag focusing for additive manufacturing of thin, narrow conductive lines
Summary
Summary
We report the design, modelling, and proof-of-concept demonstration of a continuously fed, atmospheric-pressure microplasma metal sputterer that is capable of printing conductive lines narrower than the width of the target without the need for post-processing or lithographic patterning. Ion drag-induced focusing is harnessed to print narrow lines; the focusing mechanism...
Key Challenges and Prospects for Optical Standoff Trace Detection of Explosives
Summary
Summary
Sophisticated improvised explosive devices (IEDs) challenge the capabilities of current sensors, particularly in areas away from static checkpoints. This security gap could be filled by standoff chemical sensors that detect IEDs based on external trace explosive residues. Unfortunately, previous efforts have not led to widely deployed capabilities. Crucially, the physical...
Bioelectronic measurement and feedback control of molecules in living cells
Summary
Summary
We describe an electrochemical measurement technique that enables bioelectronic measurements of reporter proteins in living cells as an alternative to traditional optical fluorescence. Using electronically programmable microfluidics, the measurement is in turn used to control the concentration of an inducer input that regulates production of the protein from a genetic...
Flexible glucose sensors and fuel cells for bioelectronic implants
Summary
Summary
Microfabrication techniques were developed to create flexible 24 um thick glucose sensors on polyimide substrates. Measurements of the sensor performance, recorded as voltage potential, were carried out for a range of glucose concentrations (0 – 8 mM) in physiological saline (0.1 M NaCl, pH 7.4). The sensors show rapid response...
Fluidic microoptics with adjustable focusing and beam steering for single cell optogenetics
Summary
Summary
Electrically controlled micron-scale liquid lenses have been designed, fabricated and demonstrated, that provide both adjustable focusing and beam steering, with the goal of applying them to optogenetic in vivo mapping of brain activity with single cell resolution. The liquid lens is formed by the interface between two immiscible liquids which...
Use of mass spectrometric vapor analysis to improve canine explosive detection efficiency
Summary
Summary
Canines remain the gold standard for explosives detection in many situations, and there is an ongoing desire for them to perform at the highest level. This goal requires canine training to be approached similarly to scientific sensor design. Developing a canine training regimen is made challenging by a lack of...
Open-source, community-driven microfluidics with Metafluidics
Summary
Summary
Microfluidic devices have the potential to automate and miniaturize biological experiments, but open-source sharing of device designs has lagged behind sharing of other resources such as software. Synthetic biologists have used microfluidics for DNA assembly, cell-free expression, and cell culture, but a combination of expense, device complexity, and reliance on...
Re-engineering Artificial Muscle with Microhydraulics
Summary
fraction of their length. The 100 μm pitch MSA presented here already has an output power density of over 200 W kg− 1, rivaling the most powerful biological muscles, due to the scaling of surface tension forces, MSA’s power density grows quadratically as its dimensions are reduced.
Summary
We introduce a new type of actuator, the microhydraulic stepping actuator (MSA), which borrows design and operational concepts from biological muscle and stepper motors. MSAs offer a unique combination of power, efficiency, and scalability not easily achievable on the microscale. The actuator works by integrating surface tension forces produced by...
Raman Detection of a Single Airborne Aerosol Particles of Isovanillin(3.09 MB)
Summary
Summary
Raman spectroscopy of trapped single aerosol particles has been reported previously. However, detection of single aerosol particles via Raman spectroscopy in a flowing system has not been yet reported. In this paper, we describe the first detection of single 3 um flowing airborne aerosol particles flowing through a Raman system...
Strong effect of azodye layer thickness on RM-stabilized photoalignment
Summary
Summary
We have previously proposed a process for stabilizing azodye photo-alignment layers using a surface localized reactive mesogen (RM) layer applied by dissolving the monomer in a liquid crystal prior to filling the cell. Surprisingly, thin azodye layers (~3 nm) exhibit improved stability upon exposure to polarized light compared to thicker...