Two metabolic factors linked to liver disease

MedPage reports on a recent study finding that the presence of two or more metabolic risk factors was associated with greater odds of steatosis and fibrosis. The study was authored by Kajal Claypool, in the Laboratory's Chemical and Biological Technologies Group; Michelle T. Long MD, MSc, of the Boston University School of Medicine; and Chirag J. Patel of Harvard Medical School.

Among over 4,000 participants, those who had at least two metabolic factors based on metabolic-associated fatty liver disease (MAFLD) criteria were at significantly higher risk of developing steatosis (adjusted odds ratio [aOR] 5.79, 95% CI 3.98-8.43) and fibrosis (aOR 2.5, 95% CI 1.3-4.81), independent of high body mass index and diabetes status.